Curiosity is also the opposite of shame.
Fear and shame operate in the limbic system, the more primal engines of our neurology. Curiosity operates in the frontal cortex, the more recent and analytical aspects of our neurology.
Fear solicits a problem responding module, the “fight, flight, or faint” system. Curiosity invokes a problem solving module. Courage can be a positive counterbalance to fear. Curiosity, however, is a cure to fear.